Quartigod eldest daughter of Amenhotep III by Tiye. Elevated to Great Royal Wife of her own father in the period of his First Sed Festival (year 30, c. 1361 BCE) — the canonical Egyptian-pharaonic father-daughter Royal-Marriage that paralleled the divine-renewal Sed Festival. The Sitamun chair found in the tomb of her maternal grandparents Yuya and Tjuyu (KV46) bears her Great Royal Wife titulary.